Stress psoriasis: the psychological mechanism behind the disease

    Stress psoriasis: the psychological mechanism behind the disease

    La Psoriasis is a chronic disease of
    skin that is not contagious and that shows itself with a series of lesions
    superficial scaly. According to the National Psoriasis Foundation of the USA
    , between 1 and 3% of the world population suffers from it.

    It is certain that still
    the causes of psoriasis are not entirely clear; many experts coincide that
    would be due to a too high rate of mitosis of the cells of the
    skin. But… what is this anomaly due to? The answers to these questions are
    very different, some theories refer to a system defect
    immune, genetic predisposition and environmental factors such as stress. But apart from the causes
    of the disease, it is known that psoriasis has a very high component
    psychological, to the point that it is considered one of the main diseases
    psychosomatic, which is why some specialists have established one
    distinction speaking of psoriasis from
    stress
    . As early as 1990 Faber
    postulated that stress played a role in the pathogenesis of psoriasis. This
    researcher pointed out that some facts such as: the symmetry of the lesions, the aggravation
    following nervous stress and remission after dissecting some nerves
    peripheral, were aspects that were closely linked with the System
    Nervous. Thus, he hypothesized that the release of substance P (a peptide that
    acts as a neurotransmitter and would be involved in pain mechanisms)
    would be responsible for the course of the disease. A study
    posterior found that psoriasis was actually due to the action
    joint of different neuro-peptides and not only to substance P, although, this one
    idea is not shared by the whole scientific community. So, these
    researchers consider that following a prolonged stressful situation,
    our organism would release one extra-neuronal level, in the skin
    series of neuro-peptides that would be responsible for accelerating development
    of the disease. But if we want
    delving into psychological functioning, there are many experts who
    coincide in affirming that a vicious circle is created in which stress
    (due to factors alien to the disease) plays an essential role in the appearance
    of psoriasis and subsequently the stress experienced since the appearance of the
    pathology itself causes this to worsen. Another given to
    support of the theory of stress as a trigger and aggravating factor of
    condition, is the compatibility between psoriasis and other ailments eminently
    psychological such as: - The Depression:
    in people with psoriasis it is found between 10 and 33% (of which 5% has
    suicidal intentions) of the cases, compared to 10 or 12% found
    in the unaffected population. - Anxiety: Yes
    manifests itself in people suffering from psoriasis to an extent between 38 and
    40%, while the population not affected by psoriasis presents anxiety only in
    25% of cases. If we refer to
    other pathologies whose psychological component has been amply demonstrated
    in the scientific literature, it can be found that 26% of people with
    psoriasis also suffers from high blood pressure and 17% of ailments
    gastrointestinal. To these data goes
    added a recent research carried out by the University of Murcia (Spain),
    in which it was found that people with psoriasis presented
    certain personological peculiarities that differentiated them from the rest of the
    population. These peculiarities would make people not capable
    to fight stress, highlighting a series of emotional responses
    maladaptive. For example, a high vulnerability was found in the face
    to stress, essentially other-oriented behavior in the
    attempt to avoid social friction but which at the same time affects the
    own responses to stressful situations and a difficulty
    particularly in regulating emotions, which would score very high
    in the scale of the alexithymia. Yes is
    also appreciated a very low index of adaptation in the face of situations
    stressors and elevated indicators of neurosis. At the same time,
    It has been shown that people with psoriasis have high scores in
    evidence of attempts to avoid pain, an idea later demonstrated
    by University of Manchester researchers, according to whom the people who
    suffering from this pathology would develop an implying mechanism
    brain changes in the insular cortex that allows them to
    respond in a more attenuated way in the face of feelings of disgust. In summary, the
    psoriasis is not just a pathology determined in a particular way by the levels
    of stress and maladaptive behaviors, but at the same time, the same
    disease produces changes in the brain that would cause these
    people react differently to certain environmental and social stimuli.
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