Could stress trigger a neurological event? Can a prolonged state of anxiety cause a heart attack? How does depression affect physical health? These and other questions represent a fairly common state of restlessness among people. This has been my line of research for at least three years, so I have had to face many more or less incredulous people; people who firmly believe that emotional states par excellence facilitate the onset and course of the most varied diseases and other professionals who still continue to talk about psychosomatic diseases, a definition that I firmly believe should be eliminated from the vocabulary because absolutely ALL diseases have in some way a psychosomatic component. Recently a title crossed the pages of some world newspapers: “La trough it is as deadly a risk factor as smoking, ”the idea is not new but new scientific data are always welcome. The study was carried out by the University of Bergen in Norway and King's College in London. The scholars used the data corresponding to interviews carried out with 60 people, relating them to the corresponding mortality rates. They found that, over a four-year period, the risk of mortality increased at a similar rate among people suffering from trough and those who were smokers. The analyzes went further showing that people who suffered from combined states of trough e anxiety they were at less risk than those who only suffered from depression. Thus, we would refer to two different risk groups: people with high levels of anxiety are more vulnerable to suffering from cerebrovascular accidents and cardiovascular attacks than people with trough have a tendency to deny their symptoms so they usually do not seek help to solve their physical problems by taking unnecessary risks that predict a high mortality In 2001 Ostir, presented a study carried out with 2.478 volunteers which demonstrated with sufficient precision that those people who scored higher on the emotional well-being scale had a much lower tendency to suffer from cerebrovascular accidents. Later, in 2002, Tarangano, studying 478 people over a period of 19 months showed that theanxiety increases the risk of vascular damage. The presence of anxiety mild and moderate over long periods of time increases the risk nine times. But… what is the emotional state that causes the most damage? There is no emotional state that a priori is more harmful but rather it can be said that each emotion plays a different role in various diseases. For example, there are two essential factors for a cerebrovascular accident, understood as cerebrovascular infarction, haemorrhage or transient ischemia, to appear: the inability to relax (recurrent and negative thoughts that cause anxiety) and a negative attitude in dealing with stressful situations (characterized by directly facing stress without analyzing the consequences of actions which generates even more stress). Logically, the emotional consequence for the person is the fall into a great state ofanxiety which can easily lead to a life-threatening disease such as a cerebrovascular accident or a cardiovascular attack. L'anxiety it shows itself many times as a trigger for the most diverse diseases while the trough it relates more to the course of the pathology. It is well known that pessimism and the trough they increase the period of convalescence, both after a surgical operation and after a common common bronchitis, since they act by reducing the body's natural defenses. Of course, it must be emphasized that the existence of emotional states of any kind is not a sufficient factor to cause disease, at the base there will always be risk factors at a physiological level.